Dramatic Response of Lupus Enteritis, Nephritis, and Pancytopenia to Plasmapheresis and Rituximab

Dramatic Response of Lupus Enteritis, Nephritis, and Pancytopenia to Plasmapheresis and Rituximab

Blog Article

Background.Although lupus enteritis is a rare manifestation of systemic lupus erythematosus yet results in significant distress.This disorder contributes to diagnostic and therapeutic dilemma leading to enhanced mortality.Case Description.

We report a case history of a 29-year-old female who presented with severe abdominal pain, watery stools, and vomiting, and later on, she developed pancytopenia and renal impairment.On intensive workup, diagnosis of lupus-associated enteritis, nephritis, Footwear and pancytopenia was discovered.She improved drastically on initiation of plasmapheresis followed by low-dose intravenous rituximab.One year posttreatment, she remained in complete remission.

Conclusion.From this case, it can be suggested that in a young female with intractable abdominal pain, the Horse Chest Buckles remote possibility of lupus enteritis must be kept in mind.Besides this, plasmapheresis can have a potential role in refractory lupus enteritis.Furthermore, low-dose intravenous rituximab can be a safe and cost-effective treatment option in achieving sustained remission of clinical and laboratory parameters in lupus enteritis.